pronetalol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
aromatic ring -CH(-OH)-CH2-NH-R 2289 54-80-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pronethalol
  • (+/-)-Pronethalol
  • naphthylisoproterenol
  • nethalide
  • pronetalol
  • DL-Pronethalol
  • pronethalol hydrochloride
  • pronethalol HCl
  • Molecular weight: 229.32
  • Formula: C15H19NO
  • CLOGP: 2.59
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 2
  • TPSA: 32.26
  • ALOGS: -3.35
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.23 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Beta-2 adrenergic receptor GPCR Kd 6.80 CHEMBL

External reference:

IDSource
C0033424 UMLSCUI
CHEBI:8463 CHEBI
CHEMBL16476 ChEMBL_ID
C084832 MESH_SUPPLEMENTAL_RECORD_UI
1580 INN_ID
51-02-5 SECONDARY_CAS_RN
XBP4RT1IMQ UNII
4930 PUBCHEM_CID
001851 NDDF

Pharmaceutical products:

None